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Neurophysiological Defects and Neuronal Gene Deregulation in Drosophila mir-124 Mutants
miR-124 is conserved in sequence and neuronal expression across the animal kingdom and is predicted to have hundreds of mRNA targets. Diverse defects in neural development and function were reported from miR-124 antisense studies in vertebrates, but a nematode knockout of mir-124 surprisingly lacked...
Autores principales: | Sun, Kailiang, Westholm, Jakub Orzechowski, Tsurudome, Kazuya, Hagen, Joshua W., Lu, Yubing, Kohwi, Minoree, Betel, Doron, Gao, Fen-Biao, Haghighi, A. Pejmun, Doe, Chris Q., Lai, Eric C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276548/ https://www.ncbi.nlm.nih.gov/pubmed/22347817 http://dx.doi.org/10.1371/journal.pgen.1002515 |
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