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Rewiring of PDZ Domain-Ligand Interaction Network Contributed to Eukaryotic Evolution

PDZ domain-mediated interactions have greatly expanded during metazoan evolution, becoming important for controlling signal flow via the assembly of multiple signaling components. The evolutionary history of PDZ domain-mediated interactions has never been explored at the molecular level. It is of gr...

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Detalles Bibliográficos
Autores principales: Kim, Jinho, Kim, Inhae, Yang, Jae-Seong, Shin, Young-Eun, Hwang, Jihye, Park, Solip, Choi, Yoon Sup, Kim, Sanguk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276551/
https://www.ncbi.nlm.nih.gov/pubmed/22346764
http://dx.doi.org/10.1371/journal.pgen.1002510