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Rewiring of PDZ Domain-Ligand Interaction Network Contributed to Eukaryotic Evolution
PDZ domain-mediated interactions have greatly expanded during metazoan evolution, becoming important for controlling signal flow via the assembly of multiple signaling components. The evolutionary history of PDZ domain-mediated interactions has never been explored at the molecular level. It is of gr...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276551/ https://www.ncbi.nlm.nih.gov/pubmed/22346764 http://dx.doi.org/10.1371/journal.pgen.1002510 |