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The Dynamics and Prognostic Potential of DNA Methylation Changes at Stem Cell Gene Loci in Women's Cancer

Aberrant DNA methylation is an important cancer hallmark, yet the dynamics of DNA methylation changes in human carcinogenesis remain largely unexplored. Moreover, the role of DNA methylation for prediction of clinical outcome is still uncertain and confined to specific cancers. Here we perform the m...

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Detalles Bibliográficos
Autores principales: Zhuang, Joanna, Jones, Allison, Lee, Shih-Han, Ng, Esther, Fiegl, Heidi, Zikan, Michal, Cibula, David, Sargent, Alexandra, Salvesen, Helga B., Jacobs, Ian J., Kitchener, Henry C., Teschendorff, Andrew E., Widschwendter, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276553/
https://www.ncbi.nlm.nih.gov/pubmed/22346766
http://dx.doi.org/10.1371/journal.pgen.1002517