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Kava Components Down-Regulate Expression of AR and AR Splice Variants and Reduce Growth in Patient-Derived Prostate Cancer Xenografts in Mice

Men living in Fiji and drinking kava have low incidence of prostate cancer (PCa). However, the PCa incidence among Fijian men who had migrated to Australia, increased by 5.1-fold. We therefore examined the potential effects of kava root extracts and its active components (kavalactones and flavokawai...

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Detalles Bibliográficos
Autores principales: Li, Xuesen, Liu, Zhongbo, Xu, Xia, Blair, Christopher A., Sun, Zheng, Xie, Jun, Lilly, Michael B., Zi, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276576/
https://www.ncbi.nlm.nih.gov/pubmed/22347450
http://dx.doi.org/10.1371/journal.pone.0031213