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ALK-Activating Homologous Mutations in LTK Induce Cellular Transformation

Leukocyte tyrosine kinase (LTK) is a receptor tyrosine kinase reported to be overexpressed in human leukemia. Though much regarding the function of LTK remains unknown, it shares a high degree of similarity with anaplastic lymphoma kinase (ALK), which is found mutated in human cancer. In order to de...

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Detalles Bibliográficos
Autores principales: Roll, J. Devon, Reuther, Gary W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276580/
https://www.ncbi.nlm.nih.gov/pubmed/22347506
http://dx.doi.org/10.1371/journal.pone.0031733