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Genotype Probabilities at Intermediate Generations in the Construction of Recombinant Inbred Lines

The mouse Collaborative Cross (CC) is a panel of eight-way recombinant inbred lines: eight diverse parental strains are intermated, followed by repeated sibling mating, many times in parallel, to create a new set of inbred lines whose genomes are random mosaics of the genomes of the original eight s...

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Detalles Bibliográficos
Autor principal: Broman, Karl W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276635/
https://www.ncbi.nlm.nih.gov/pubmed/22345609
http://dx.doi.org/10.1534/genetics.111.132647