MYC Gene Amplification is Often Acquired in Lethal Distant Breast Cancer Metastases of Unamplified Primary Tumors

In breast cancer, amplification of MYC is consistently observed in aggressive forms of disease and correlates with poor prognosis and distant metastases. However, to date, a systematic analysis of MYC amplification in metastatic breast cancers has not been reported. Specifically, whether the MYC amp...

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Detalles Bibliográficos
Autores principales: Singhi, Aatur D., Cimino-Mathews, Ashley, Jenkins, Robert B., Lan, Fusheng, Fink, Stephanie R., Nassar, Hind, Vang, Russell, Fetting, John, Hicks, Jessica, Sukumar, Saraswati, De Marzo, Angelo M., Argani, Pedram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276715/
https://www.ncbi.nlm.nih.gov/pubmed/22056952
http://dx.doi.org/10.1038/modpathol.2011.171