Hsp90 Stress Potentiates Rapid Cellular Adaptation through Induction of Aneuploidy

Aneuploidy, a state of having uneven numbers of chromosomes, is a form of large-effect mutation able to confer adaptive phenotypes under diverse stress conditions(1,2). Here we investigate whether pleiotropic stress could in turn induce aneuploidy in budding yeast. We show that while diverse stresse...

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Detalles Bibliográficos
Autores principales: Chen, Guangbo, Bradford, William D., Seidel, Chris W., Li, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276732/
https://www.ncbi.nlm.nih.gov/pubmed/22286062
http://dx.doi.org/10.1038/nature10795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276732/
https://www.ncbi.nlm.nih.gov/pubmed/22286062
http://dx.doi.org/10.1038/nature10795

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