INCREASED VASCULARITY AND SPONTANEOUS METASTASIS OF BREAST CANCER BY HEDGEHOG SIGNALING MEDIATED UPREGULATION OF CYR61

The Hedgehog (Hh) pathway is well known for its involvement in angiogenesis and vasculogenesis during ontogeny. The ligand, Sonic hedgehog (SHH), plays an important role in vascular formation during development. However, SHH expression is upregulated on tumor cells and can impact the tumor microenvi...

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Detalles Bibliográficos
Autores principales: Harris, Lillianne G., Pannell, Lewis K., Singh, Seema, Samant, Rajeev S., Shevde, Lalita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276742/
https://www.ncbi.nlm.nih.gov/pubmed/22056874
http://dx.doi.org/10.1038/onc.2011.496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276742/
https://www.ncbi.nlm.nih.gov/pubmed/22056874
http://dx.doi.org/10.1038/onc.2011.496

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