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Effects of quetiapine and sertindole on subchronic ketamine-induced deficits in attentional set-shifting in rats

RATIONALE: Prefrontal cortical dysfunctions, including an impaired ability to shift perceptual attentional set, are core features of schizophrenia. Nevertheless, the effectiveness of second-generation antipsychotic drugs in treating specific prefrontal dysfunctions remains equivocal. OBJECTIVES: To...

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Detalles Bibliográficos
Autores principales: Nikiforuk, Agnieszka, Popik, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276756/
https://www.ncbi.nlm.nih.gov/pubmed/21918808
http://dx.doi.org/10.1007/s00213-011-2487-x