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LRRK2 in Transcription and Translation Regulation: Relevance for Parkinson’s Disease
Parkinson’s disease (PD) is the most common neurodegenerative movement disorder and is characterized by the selective loss of dopaminergic neurons and the presence of Lewy bodies. Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most frequent cause of both familial and sporadic PD....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Research Foundation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276974/ https://www.ncbi.nlm.nih.gov/pubmed/22363314 http://dx.doi.org/10.3389/fneur.2012.00012 |