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Association of CYP3A5*3 polymorphism with development of acute leukemia

BACKGROUND: CYP3A5 was observed to be an important genetic contributor to inter individual differences in CYP3A-dependent drug metabolism in acute leukemic patients. Loss of CYP3A5 expression was mainly conferred by a single nucleotide polymorphism at 6986A>G (CYP3A5*3). We investigated the assoc...

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Detalles Bibliográficos
Autores principales: Rao, D. Nageswara, Manjula, G., Sailaja, K., Surekha, D., Raghunadharao, D., Rajappa, Senthil, Vishnupriya, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276986/
https://www.ncbi.nlm.nih.gov/pubmed/22345989
http://dx.doi.org/10.4103/0971-6866.92098