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A Cross-Platform Genome-Wide Comparison of the Relationship of Promoter DNA Methylation to Gene Expression

Peripheral mononuclear cell preparations are commonly used as proxies for other tissues in studies of the role of gene expression and methylation in human disease. Whether changes in peripheral DNA methylation are associated with changes in peripheral blood or brain gene expression is not clear. In...

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Detalles Bibliográficos
Autores principales: Plume, Jeffrey M., Beach, S. R. H., Brody, Gene H., Philibert, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277264/
https://www.ncbi.nlm.nih.gov/pubmed/22363339
http://dx.doi.org/10.3389/fgene.2012.00012