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Experimental Mapping of the Canine KCNJ2 and KCNJ12 Gene Structures and Functional Analysis of the Canine K(IR)2.2 ion Channel

For many model organisms traditionally in use for cardiac electrophysiological studies, characterization of ion channel genes is lacking. We focused here on two genes encoding the inward rectifier current, KCNJ2 and KCNJ12, in the dog heart. A combination of RT-PCR, 5′-RACE, and 3′-RACE demonstrated...

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Detalles Bibliográficos
Autores principales: Houtman, Marien J. C., Takanari, Hiroki, Kok, Bart G. J. M., van Eck, Margot, Montagne, Denise R., Vos, Marc A., de Boer, Teun P., van der Heyden, Marcel A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277267/
https://www.ncbi.nlm.nih.gov/pubmed/22363290
http://dx.doi.org/10.3389/fphys.2012.00009