TGF-β1 modulates the homeostasis between MMPs and MMP inhibitors through p38 MAPK and ERK1/2 in highly invasive breast cancer cells

BACKGROUND: Metastasis is the main factor responsible for death in breast cancer patients. Matrix metalloproteinases (MMPs) and their inhibitors, known as tissue inhibitors of MMPs (TIMPs), and the membrane-associated MMP inhibitor (RECK), are essential for the metastatic process. We have previously...

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Detalles Bibliográficos
Autores principales: Gomes, Luciana R, Terra, Letícia F, Wailemann, Rosângela AM, Labriola, Leticia, Sogayar, Mari C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277461/
https://www.ncbi.nlm.nih.gov/pubmed/22260435
http://dx.doi.org/10.1186/1471-2407-12-26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277461/
https://www.ncbi.nlm.nih.gov/pubmed/22260435
http://dx.doi.org/10.1186/1471-2407-12-26

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