Bacillus anthracis-derived edema toxin (ET) counter-regulates movement of neutrophils and macromolecules through the endothelial paracellular pathway

BACKGROUND: A common finding amongst patients with inhalational anthrax is a paucity of polymorphonuclear leukocytes (PMNs) in infected tissues in the face of abundant circulating PMNs. A major virulence determinant of anthrax is edema toxin (ET), which is formed by the combination of two proteins p...

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Detalles Bibliográficos
Autores principales: Nguyen, Chinh, Feng, Chiguang, Zhan, Min, Cross, Alan S, Goldblum, Simeon E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277462/
https://www.ncbi.nlm.nih.gov/pubmed/22230035
http://dx.doi.org/10.1186/1471-2180-12-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277462/
https://www.ncbi.nlm.nih.gov/pubmed/22230035
http://dx.doi.org/10.1186/1471-2180-12-2

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