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Bacillus anthracis-derived edema toxin (ET) counter-regulates movement of neutrophils and macromolecules through the endothelial paracellular pathway
BACKGROUND: A common finding amongst patients with inhalational anthrax is a paucity of polymorphonuclear leukocytes (PMNs) in infected tissues in the face of abundant circulating PMNs. A major virulence determinant of anthrax is edema toxin (ET), which is formed by the combination of two proteins p...
Autores principales: | Nguyen, Chinh, Feng, Chiguang, Zhan, Min, Cross, Alan S, Goldblum, Simeon E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277462/ https://www.ncbi.nlm.nih.gov/pubmed/22230035 http://dx.doi.org/10.1186/1471-2180-12-2 |
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