Cargando…

Expression QTL mapping in regulatory and helper T cells from the BXD family of strains reveals novel cell-specific genes, gene-gene interactions and candidate genes for auto-immune disease

BACKGROUND: Regulatory T cells (Tregs) play an essential role in the control of the immune response. Treg cells represent important targets for therapeutic interventions of the immune system. Therefore, it will be very important to understand in more detail which genes are specifically activated in...

Descripción completa

Detalles Bibliográficos
Autores principales: Alberts, Rudi, Chen, Hairong, Pommerenke, Claudia, Smit, August B, Spijker, Sabine, Williams, Robert W, Geffers, Robert, Bruder, Dunja, Schughart, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277499/
https://www.ncbi.nlm.nih.gov/pubmed/22182475
http://dx.doi.org/10.1186/1471-2164-12-610