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Immunization against Leishmania major Infection Using LACK- and IL-12-Expressing Lactococcus lactis Induces Delay in Footpad Swelling

BACKGROUND: Leishmania is a mammalian parasite affecting over 12 million individuals worldwide. Current treatments are expensive, cause severe side effects, and emerging drug resistance has been reported. Vaccination is the most cost-effective means to control infectious disease but currently there...

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Detalles Bibliográficos
Autores principales: Hugentobler, Felix, Yam, Karen K., Gillard, Joshua, Mahbuba, Raya, Olivier, Martin, Cousineau, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277590/
https://www.ncbi.nlm.nih.gov/pubmed/22348031
http://dx.doi.org/10.1371/journal.pone.0030945