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Kinetochore-Dependent Microtubule Rescue Ensures Their Efficient and Sustained Interactions in Early Mitosis

How kinetochores regulate microtubule dynamics to ensure proper kinetochore-microtubule interactions is unknown. Here, we studied this during early mitosis in Saccharomyces cerevisiae. When a microtubule shrinks and its plus end reaches a kinetochore bound to its lateral surface, the microtubule end...

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Detalles Bibliográficos
Autores principales: Gandhi, Sapan R., Gierliński, Marek, Mino, Akihisa, Tanaka, Kozo, Kitamura, Etsushi, Clayton, Lesley, Tanaka, Tomoyuki U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277888/
https://www.ncbi.nlm.nih.gov/pubmed/22075150
http://dx.doi.org/10.1016/j.devcel.2011.09.006