Regulated ATF5 loss-of-function in adult mice blocks formation and causes regression/eradication of gliomas

Glioblastomas are among the most incurable cancers. Our past findings indicated that glioblastoma cells, but not neurons or glia, require the transcription factor ATF5 (activating transcription factor 5) for survival. However, it was unknown whether interference with ATF5 function can prevent or pro...

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Detalles Bibliográficos
Autores principales: Arias, A, Lamé, M W, Santarelli, L, Hen, R, Greene, L A, Angelastro, J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277917/
https://www.ncbi.nlm.nih.gov/pubmed/21725368
http://dx.doi.org/10.1038/onc.2011.276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277917/
https://www.ncbi.nlm.nih.gov/pubmed/21725368
http://dx.doi.org/10.1038/onc.2011.276

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