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CyPPA, a Positive SK3/SK2 Modulator, Reduces Activity of Dopaminergic Neurons, Inhibits Dopamine Release, and Counteracts Hyperdopaminergic Behaviors Induced by Methylphenidate(1)

Dopamine (DA) containing midbrain neurons play critical roles in several psychiatric and neurological diseases, including schizophrenia and attention deficit hyperactivity disorder, and the substantia nigra pars compacta neurons selectively degenerate in Parkinson’s disease. Pharmacological modulati...

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Detalles Bibliográficos
Autores principales: Herrik, Kjartan F., Redrobe, John P., Holst, Dorte, Hougaard, Charlotte, Sandager-Nielsen, Karin, Nielsen, Alexander N., Ji, Huifang, Holst, Nina M., Rasmussen, Hanne B., Nielsen, Elsebet Ø., Strøbæk, Dorte, Shepard, Paul D., Christophersen, Palle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278045/
https://www.ncbi.nlm.nih.gov/pubmed/22347859
http://dx.doi.org/10.3389/fphar.2012.00011