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CyPPA, a Positive SK3/SK2 Modulator, Reduces Activity of Dopaminergic Neurons, Inhibits Dopamine Release, and Counteracts Hyperdopaminergic Behaviors Induced by Methylphenidate(1)
Dopamine (DA) containing midbrain neurons play critical roles in several psychiatric and neurological diseases, including schizophrenia and attention deficit hyperactivity disorder, and the substantia nigra pars compacta neurons selectively degenerate in Parkinson’s disease. Pharmacological modulati...
Autores principales: | Herrik, Kjartan F., Redrobe, John P., Holst, Dorte, Hougaard, Charlotte, Sandager-Nielsen, Karin, Nielsen, Alexander N., Ji, Huifang, Holst, Nina M., Rasmussen, Hanne B., Nielsen, Elsebet Ø., Strøbæk, Dorte, Shepard, Paul D., Christophersen, Palle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278045/ https://www.ncbi.nlm.nih.gov/pubmed/22347859 http://dx.doi.org/10.3389/fphar.2012.00011 |
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