The monoclonal antibody to cytotoxic T lymphocyte antigen 4, ipilimumab, in the treatment of melanoma

BACKGROUND: Cytotoxic T lymphocyte antigen 4 (CTLA-4) is an inhibitory regulator of the T-cell immune response against tumor cells. Ipilimumab is a monoclonal antibody directed against CTLA-4. OBJECTIVE: This review describes the basic mechanism of ipilimumab and discusses data available to date wit...

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Detalles Bibliográficos
Autor principal: Verschraegen, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278204/
https://www.ncbi.nlm.nih.gov/pubmed/22346364
http://dx.doi.org/10.2147/CMAR.S15551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278204/
https://www.ncbi.nlm.nih.gov/pubmed/22346364
http://dx.doi.org/10.2147/CMAR.S15551

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