Synthesis, characterization, and in vivo efficacy evaluation of PGG–docetaxel conjugate for potential cancer chemotherapy

AIM: This work is intended to develop and evaluate a biopolymeric poly(L-γ-glutamylglutamine) (PGG)–docetaxel (DTX) conjugate that can spontaneously self-assemble in aqueous solutions to become nanoparticles. METHODS: DTX was covalently attached to hydrophilic PGG by direct esterification, and the c...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Danbo, Van, Sang, Shu, Yingyi, Liu, Xiaoqing, Ge, Yangfeng, Jiang, Xinguo, Jin, Yi, Yu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278226/
https://www.ncbi.nlm.nih.gov/pubmed/22334784
http://dx.doi.org/10.2147/IJN.S26842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278226/
https://www.ncbi.nlm.nih.gov/pubmed/22334784
http://dx.doi.org/10.2147/IJN.S26842

Ejemplares similares