A Triad of Lys12, Lys41, Arg78 Spatial Domain, a Novel Identified Heparin Binding Site on Tat Protein, Facilitates Tat-Driven Cell Adhesion

Tat protein, released by HIV-infected cells, has a battery of important biological effects leading to distinct AIDS-associated pathologies. Cell surface heparan sulfate protoglycans (HSPGs) have been accepted as endogenous Tat receptors, and the Tat basic domain has been identified as the heparin bi...

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Detalles Bibliográficos
Autores principales: Ai, Jing, Xin, Xianliang, Zheng, Mingyue, Wang, Shuai, Peng, Shuying, Li, Jing, Wang, Limei, Jiang, Hualiang, Geng, Meiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278312/
https://www.ncbi.nlm.nih.gov/pubmed/22423313
http://dx.doi.org/10.1371/journal.pone.0002662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278312/
https://www.ncbi.nlm.nih.gov/pubmed/22423313
http://dx.doi.org/10.1371/journal.pone.0002662

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