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Chronic fluoxetine treatment in middle-aged rats induces changes in the expression of plasticity-related molecules and in neurogenesis

BACKGROUND: Antidepressants promote neuronal structural plasticity in young-adult rodents, but little is known of their effects on older animals. The polysialylated form of the neural cell adhesion molecule (PSA-NCAM) may mediate these structural changes through its anti-adhesive properties. PSA-NCA...

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Detalles Bibliográficos
Autores principales: Guirado, Ramon, Sanchez-Matarredona, David, Varea, Emilo, Crespo, Carlos, Blasco-Ibáñez, José Miguel, Nacher, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278353/
https://www.ncbi.nlm.nih.gov/pubmed/22221403
http://dx.doi.org/10.1186/1471-2202-13-5