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Magel2, a Prader-Willi syndrome candidate gene, modulates the activities of circadian rhythm proteins in cultured cells

BACKGROUND: The Magel2 gene is most highly expressed in the suprachiasmatic nucleus of the hypothalamus, where its expression cycles in a circadian pattern comparable to that of clock-controlled genes. Mice lacking the Magel2 gene have hypothalamic dysfunction, including circadian defects that inclu...

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Detalles Bibliográficos
Autores principales: Devos, Julia, Weselake, Sara V, Wevrick, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278377/
https://www.ncbi.nlm.nih.gov/pubmed/22208286
http://dx.doi.org/10.1186/1740-3391-9-12