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Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol induced steatohepatitis in mice

BACKGROUND: Peroxisome proliferator activated receptor alpha (PPARα) regulates lipids metabolism and inhibits inflammatory response. However, the role of PPARα in alcoholic liver disease is largely unknown. We aim to elucidate the effect and the molecular basis of PPARα in ethanol induced hepatic in...

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Detalles Bibliográficos
Autores principales: Kong, Lingbo, Ren, Weiguang, Li, Wencong, Zhao, Suxian, Mi, Hongmei, Wang, Rongqi, Zhang, Yuguo, Wu, Wenjuan, Nan, Yuemin, Yu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278384/
https://www.ncbi.nlm.nih.gov/pubmed/22208561
http://dx.doi.org/10.1186/1476-511X-10-246