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Shiga Toxin Binding to Glycolipids and Glycans

BACKGROUND: Immunologically distinct forms of Shiga toxin (Stx1 and Stx2) display different potencies and disease outcomes, likely due to differences in host cell binding. The glycolipid globotriaosylceramide (Gb3) has been reported to be the receptor for both toxins. While there is considerable dat...

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Detalles Bibliográficos
Autores principales: Gallegos, Karen M., Conrady, Deborah G., Karve, Sayali S., Gunasekera, Thusitha S., Herr, Andrew B., Weiss, Alison A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278406/
https://www.ncbi.nlm.nih.gov/pubmed/22348006
http://dx.doi.org/10.1371/journal.pone.0030368