Inhibition of Post-Synaptic Kv7/KCNQ/M Channels Facilitates Long-Term Potentiation in the Hippocampus

Activation of muscarinic acetylcholine receptors (mAChR) facilitates the induction of synaptic plasticity and enhances cognitive function. In the hippocampus, M(1) mAChR on CA1 pyramidal cells inhibit both small conductance Ca(2+)-activated KCa2 potassium channels and voltage-activated Kv7 potassium...

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Detalles Bibliográficos
Autores principales: Petrovic, Milos M., Nowacki, Jakub, Olivo, Valeria, Tsaneva-Atanasova, Krasimira, Randall, Andrew D., Mellor, Jack R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278412/
https://www.ncbi.nlm.nih.gov/pubmed/22348007
http://dx.doi.org/10.1371/journal.pone.0030402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278412/
https://www.ncbi.nlm.nih.gov/pubmed/22348007
http://dx.doi.org/10.1371/journal.pone.0030402

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