Progressive Activation of CD127+132− Recent Thymic Emigrants into Terminally Differentiated CD127−132+ T-Cells in HIV-1 Infection

AIM: HIV infection is associated with distortion of T-cell homeostasis and the IL-7/IL7R axis. Progressive infection results in loss of CD127+132− and gains in CD127−132+ CD4+ and CD8+ T-cells. We investigated the correlates of loss of CD127 from the T-cell surface to understand mechanisms underlyin...

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Detalles Bibliográficos
Autores principales: Sasson, Sarah C., Zaunders, John J., Seddiki, Nabila, Bailey, Michelle, McBride, Kristin, Koelsch, Kersten K., Merlin, Kate M., Smith, Don E., Cooper, David A., Kelleher, Anthony D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278435/
https://www.ncbi.nlm.nih.gov/pubmed/22348045
http://dx.doi.org/10.1371/journal.pone.0031148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278435/
https://www.ncbi.nlm.nih.gov/pubmed/22348045
http://dx.doi.org/10.1371/journal.pone.0031148

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