Analysis of the Fibroblast Growth Factor System Reveals Alterations in a Mouse Model of Spinal Muscular Atrophy

The monogenetic disease Spinal Muscular Atrophy (SMA) is characterized by a progressive loss of motoneurons leading to muscle weakness and atrophy due to severe reduction of the Survival of Motoneuron (SMN) protein. Several models of SMA show deficits in neurite outgrowth and maintenance of neuromus...

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Detalles Bibliográficos
Autores principales: Hensel, Niko, Ratzka, Andreas, Brinkmann, Hella, Klimaschewski, Lars, Grothe, Claudia, Claus, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278439/
https://www.ncbi.nlm.nih.gov/pubmed/22348054
http://dx.doi.org/10.1371/journal.pone.0031202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278439/
https://www.ncbi.nlm.nih.gov/pubmed/22348054
http://dx.doi.org/10.1371/journal.pone.0031202

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