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β-defensin 2 as an Adjuvant Promotes Anti-Melanoma Immune Responses and Inhibits the Growth of Implanted Murine Melanoma In Vivo

β-defensin 2 is a small antimicrobial peptide of the innate immune system and has been thought to regulate anti-tumor immunity. However, little is known on whether β-defensin 2 could modulate melanoma-specific NK and T cell responses. In this study, we first cloned the murine β-defensin 2 gene by RT...

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Detalles Bibliográficos
Autores principales: Mei, Han-fang, Jin, Xiao-bao, Zhu, Jia-yong, Zeng, Ai-hua, Wu, Qiang, Lu, Xue-mei, Li, Xiao-bo, Shen, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278441/
https://www.ncbi.nlm.nih.gov/pubmed/22348070
http://dx.doi.org/10.1371/journal.pone.0031328