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β-defensin 2 as an Adjuvant Promotes Anti-Melanoma Immune Responses and Inhibits the Growth of Implanted Murine Melanoma In Vivo
β-defensin 2 is a small antimicrobial peptide of the innate immune system and has been thought to regulate anti-tumor immunity. However, little is known on whether β-defensin 2 could modulate melanoma-specific NK and T cell responses. In this study, we first cloned the murine β-defensin 2 gene by RT...
Autores principales: | Mei, Han-fang, Jin, Xiao-bao, Zhu, Jia-yong, Zeng, Ai-hua, Wu, Qiang, Lu, Xue-mei, Li, Xiao-bo, Shen, Juan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278441/ https://www.ncbi.nlm.nih.gov/pubmed/22348070 http://dx.doi.org/10.1371/journal.pone.0031328 |
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