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Curcumin Promotes A-beta Fibrillation and Reduces Neurotoxicity in Transgenic Drosophila

The pathology of Alzheimer's disease (AD) is characterized by the presence of extracellular deposits of misfolded and aggregated amyloid-β (Aβ) peptide and intraneuronal accumulation of tangles comprised of hyperphosphorylated Tau protein. For several years, the natural compound curcumin has be...

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Detalles Bibliográficos
Autores principales: Caesar, Ina, Jonson, Maria, Nilsson, K. Peter R., Thor, Stefan, Hammarström, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278449/
https://www.ncbi.nlm.nih.gov/pubmed/22348084
http://dx.doi.org/10.1371/journal.pone.0031424