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Curcumin Promotes A-beta Fibrillation and Reduces Neurotoxicity in Transgenic Drosophila
The pathology of Alzheimer's disease (AD) is characterized by the presence of extracellular deposits of misfolded and aggregated amyloid-β (Aβ) peptide and intraneuronal accumulation of tangles comprised of hyperphosphorylated Tau protein. For several years, the natural compound curcumin has be...
Autores principales: | Caesar, Ina, Jonson, Maria, Nilsson, K. Peter R., Thor, Stefan, Hammarström, Per |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278449/ https://www.ncbi.nlm.nih.gov/pubmed/22348084 http://dx.doi.org/10.1371/journal.pone.0031424 |
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