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Age-Dependent Targeting of Protein Phosphatase 1 to Ca(2+)/Calmodulin-Dependent Protein Kinase II by Spinophilin in Mouse Striatum
Mechanisms underlying age-dependent changes of dendritic spines on striatal medium spiny neurons are poorly understood. Spinophilin is an F-actin- and protein phosphatase 1 (PP1)-binding protein that targets PP1 to multiple downstream effectors to modulate dendritic spine morphology and function. We...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278457/ https://www.ncbi.nlm.nih.gov/pubmed/22348105 http://dx.doi.org/10.1371/journal.pone.0031554 |