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Age-Dependent Targeting of Protein Phosphatase 1 to Ca(2+)/Calmodulin-Dependent Protein Kinase II by Spinophilin in Mouse Striatum

Mechanisms underlying age-dependent changes of dendritic spines on striatal medium spiny neurons are poorly understood. Spinophilin is an F-actin- and protein phosphatase 1 (PP1)-binding protein that targets PP1 to multiple downstream effectors to modulate dendritic spine morphology and function. We...

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Detalles Bibliográficos
Autores principales: Baucum, Anthony J., Strack, Stefan, Colbran, Roger J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278457/
https://www.ncbi.nlm.nih.gov/pubmed/22348105
http://dx.doi.org/10.1371/journal.pone.0031554