The Role of GC-Biased Gene Conversion in Shaping the Fastest Evolving Regions of the Human Genome

GC-biased gene conversion (gBGC) is a recombination-associated evolutionary process that accelerates the fixation of guanine or cytosine alleles, regardless of their effects on fitness. gBGC can increase the overall rate of substitutions, a hallmark of positive selection. Many fast-evolving genes an...

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Detalles Bibliográficos
Autores principales: Kostka, Dennis, Hubisz, Melissa J., Siepel, Adam, Pollard, Katherine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278478/
https://www.ncbi.nlm.nih.gov/pubmed/22075116
http://dx.doi.org/10.1093/molbev/msr279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278478/
https://www.ncbi.nlm.nih.gov/pubmed/22075116
http://dx.doi.org/10.1093/molbev/msr279

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