Cargando…

The Role of GC-Biased Gene Conversion in Shaping the Fastest Evolving Regions of the Human Genome

GC-biased gene conversion (gBGC) is a recombination-associated evolutionary process that accelerates the fixation of guanine or cytosine alleles, regardless of their effects on fitness. gBGC can increase the overall rate of substitutions, a hallmark of positive selection. Many fast-evolving genes an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kostka, Dennis, Hubisz, Melissa J., Siepel, Adam, Pollard, Katherine S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278478/ https://www.ncbi.nlm.nih.gov/pubmed/22075116 http://dx.doi.org/10.1093/molbev/msr279

Ejemplares similares

A Model-Based Analysis of GC-Biased Gene Conversion in the Human and Chimpanzee Genomes
por: Capra, John A., et al.
Publicado: (2013)

Forces Shaping the Fastest Evolving Regions in the Human Genome
por: Pollard, Katherine S, et al.
Publicado: (2006)

Developmental Loci Harbor Clusters of Accelerated Regions That Evolved Independently in Ape Lineages
por: Kostka, Dennis, et al.
Publicado: (2018)

Páramo is the world's fastest evolving and coolest biodiversity hotspot
por: Madriñán, Santiago, et al.
Publicado: (2013)

Quantification of GC-biased gene conversion in the human genome
por: Glémin, Sylvain, et al.
Publicado: (2015)

GC-Biased Evolution Near Human Accelerated Regions
por: Katzman, Sol, et al.
Publicado: (2010)

Probabilities of Fitness Consequences for Point Mutations Across the Human Genome
por: Gulko, Brad, et al.
Publicado: (2015)

Genome-Wide Inference of Ancestral Recombination Graphs
por: Rasmussen, Matthew D., et al.
Publicado: (2014)

Error and Error Mitigation in Low-Coverage Genome Assemblies
por: Hubisz, Melissa J., et al.
Publicado: (2011)

Noncoding Sequences Near Duplicated Genes Evolve Rapidly
por: Kostka, Dennis, et al.
Publicado: (2010)

Mutational Biases and GC-Biased Gene Conversion Affect GC Content in the Plastomes of Dendrobium Genus
por: Niu, Zhitao, et al.
Publicado: (2017)

Bayesian inference of ancient human demography from individual genome sequences
por: Gronau, Ilan, et al.
Publicado: (2011)

Mapping gene flow between ancient hominins through demography-aware inference of the ancestral recombination graph
por: Hubisz, Melissa J., et al.
Publicado: (2020)

Evidence for Widespread GC-biased Gene Conversion in Eukaryotes
por: Pessia, Eugénie, et al.
Publicado: (2012)

GC-Content Evolution in Bacterial Genomes: The Biased Gene Conversion Hypothesis Expands
por: Lassalle, Florent, et al.
Publicado: (2015)

1000 human genomes carry widespread signatures of GC biased gene conversion
por: Dutta, Rajib, et al.
Publicado: (2018)

The fastest animals and vehicles are neither the biggest nor the fastest over lifetime
por: Bejan, A., et al.
Publicado: (2018)

Substitution Patterns Are GC-Biased in Divergent Sequences across the Metazoans
por: Capra, John A., et al.
Publicado: (2011)

The world's fastest camera
por: Piquepaille, Roland
Publicado: (2006)

GC-biased gene conversion conceals the prediction of the nearly neutral theory in avian genomes
por: Bolívar, Paulina, et al.
Publicado: (2019)

Ongoing GC-Biased Evolution Is Widespread in the Human Genome and Enriched Near Recombination Hot Spots
por: Katzman, Sol, et al.
Publicado: (2011)

Mutation bias and GC content shape antimutator invasions
por: Couce, Alejandro, et al.
Publicado: (2019)

Quantifying GC-Biased Gene Conversion in Great Ape Genomes Using Polymorphism-Aware Models
por: Borges, Rui, et al.
Publicado: (2019)

The Effects of GC-Biased Gene Conversion on Patterns of Genetic Diversity among and across Butterfly Genomes
por: Boman, Jesper, et al.
Publicado: (2021)

Patterns of Positive Selection in Six Mammalian Genomes
por: Kosiol, Carolin, et al.
Publicado: (2008)

Non-crossover gene conversions show strong GC bias and unexpected clustering in humans
por: Williams, Amy L, et al.
Publicado: (2015)

Comparative Genomic Analysis of the Streptococcus dysgalactiae Species Group: Gene Content, Molecular Adaptation, and Promoter Evolution
por: Suzuki, Haruo, et al.
Publicado: (2011)

Twisted Signatures of GC-Biased Gene Conversion Embedded in an Evolutionary Stable Karyotype
por: Mugal, Carina F., et al.
Publicado: (2013)

Biased Gene Conversion and GC-Content Evolution in the Coding Sequences of Reptiles and Vertebrates
por: Figuet, Emeric, et al.
Publicado: (2014)

CERN's fastest-ever computer arrives
Publicado: (1985)

Record of Fastest Time Made by Horses
Publicado: (1893)

Adapting Biased Gene Conversion theory to account for intensive GC-content deterioration in the human genome by novel mutations
por: Paudel, Rajan, et al.
Publicado: (2020)

Schematic for efficient computation of GC, GC3, and AT3 bias spectra of genome
por: Rizvi, Ahsan Z, et al.
Publicado: (2012)

GC bias affects genomic and metagenomic reconstructions, underrepresenting GC-poor organisms
por: Browne, Patrick Denis, et al.
Publicado: (2020)

Biased Inference of Selection Due to GC-Biased Gene Conversion and the Rate of Protein Evolution in Flycatchers When Accounting for It
por: Bolívar, Paulina, et al.
Publicado: (2018)

Evolutionary Stasis in Cycad Plastomes and the First Case of Plastome GC-Biased Gene Conversion
por: Wu, Chung-Shien, et al.
Publicado: (2015)

World's fastest network standard demonstrated at CERN
Publicado: (1999)

The Fastest Saccadic Responses Escape Visual Masking
por: Crouzet, Sébastien M., et al.
Publicado: (2014)

The fastest ball games from the viewpoint of science
por: Kondrič, Miran
Publicado: (2017)

GC3-biased gene domains in mammalian genomes
por: Shen, Wenlong, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_p815jof5f91a7vqqlv5o7coorp