Defining a role for sphingosine kinase 1 in p53-dependent tumors

p53 is a crucial tumor suppressor that is mutated or deleted in a majority of cancers. Exactly how p53 prevents tumor progression has proved elusive for many years; however, this information is crucial to define targets for chemotherapeutic development that can effectively restore p53 function. Bioa...

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Detalles Bibliográficos
Autores principales: Heffernan-Stroud, Linda A., Helke, Kristi L., Jenkins, Russell W., De Costa, Anna-Maria, Hannun, Yusuf A., Obeid, Lina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278571/
https://www.ncbi.nlm.nih.gov/pubmed/21765468
http://dx.doi.org/10.1038/onc.2011.302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278571/
https://www.ncbi.nlm.nih.gov/pubmed/21765468
http://dx.doi.org/10.1038/onc.2011.302

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