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Chronic intermittent hypoxia induces local inflammation of the rat carotid body via functional upregulation of proinflammatory cytokine pathways

Maladaptive changes in the carotid body (CB) induced by chronic intermittent hypoxia (IH) account for the pathogenesis of cardiovascular morbidity in patients with sleep-disordered breathing. We postulated that the proinflammatory cytokines, namely interleukin (IL)-1β, IL-6 and tumor necrosis factor...

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Detalles Bibliográficos
Autores principales: Lam, Siu-Yin, Liu, Yu, Ng, Kwong-Man, Lau, Chi-Fai, Liong, Emily C., Tipoe, George L., Fung, Man-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278607/
https://www.ncbi.nlm.nih.gov/pubmed/22187044
http://dx.doi.org/10.1007/s00418-011-0900-5