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SOX2 has a crucial role in the lineage determination and proliferation of mesenchymal stem cells through Dickkopf-1 and c-MYC

SOX2 is a well-known core transcription factor in embryonic stem cells (ESCs) and has an important role in the maintenance of pluripotency. Recently, SOX2 expression has also been reported in adult stem cells (ASCs), but the role of SOX2 in ASCs remains unknown. In this study, we examined the molecu...

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Detalles Bibliográficos
Autores principales: Park, S B, Seo, K W, So, A Y, Seo, M S, Yu, K R, Kang, S K, Kang, K S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278737/
https://www.ncbi.nlm.nih.gov/pubmed/22015605
http://dx.doi.org/10.1038/cdd.2011.137