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Exploiting heterogeneous features to improve in silico prediction of peptide status – amyloidogenic or non-amyloidogenic

BACKGROUND: Prediction of short stretches in protein sequences capable of forming amyloid-like fibrils is important in understanding the underlying cause of amyloid illnesses thereby aiding in the discovery of sequence-targeted anti-aggregation pharmaceuticals. Due to the constraints of experimental...

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Detalles Bibliográficos
Autores principales: Nair, Smitha Sunil Kumaran, Subba Reddy, NV, Hareesha, KS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278838/
https://www.ncbi.nlm.nih.gov/pubmed/22373069
http://dx.doi.org/10.1186/1471-2105-12-S13-S21