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In silico modification of suberoylanilide hydroxamic acid (SAHA) as potential inhibitor for class II histone deacetylase (HDAC)

BACKGROUND: The cervical cancer is the second most prevalent cancer for the woman in the world. It is caused by the oncogenic human papilloma virus (HPV). The inhibition activity of histone deacetylase (HDAC) is a potential strategy for cancer therapy. Suberoylanilide hydroxamic acid (SAHA) is widel...

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Detalles Bibliográficos
Autores principales: Tambunan, Usman SF, Bramantya, N, Parikesit, Arli A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278840/
https://www.ncbi.nlm.nih.gov/pubmed/22373132
http://dx.doi.org/10.1186/1471-2105-12-S13-S23