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Interaction with Phosphoinositides Confers Adaptation onto the TRPV1 Pain Receptor
Adaptation is a common feature of many sensory systems. But its occurrence to pain sensation has remained elusive. Here we address the problem at the receptor level and show that the capsaicin ion channel TRPV1, which mediates nociception at the peripheral nerve terminals, possesses properties essen...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279049/ https://www.ncbi.nlm.nih.gov/pubmed/19243225 http://dx.doi.org/10.1371/journal.pbio.1000046 |