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Interaction with Phosphoinositides Confers Adaptation onto the TRPV1 Pain Receptor

Adaptation is a common feature of many sensory systems. But its occurrence to pain sensation has remained elusive. Here we address the problem at the receptor level and show that the capsaicin ion channel TRPV1, which mediates nociception at the peripheral nerve terminals, possesses properties essen...

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Detalles Bibliográficos
Autores principales: Yao, Jing, Qin, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279049/
https://www.ncbi.nlm.nih.gov/pubmed/19243225
http://dx.doi.org/10.1371/journal.pbio.1000046