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TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions

BACKGROUND: The TRIM5 proteins are cellular restriction factors that prevent retroviral infection in a species-specific manner. Multiple experiments indicate that restriction activity requires accessory host factors, including E2-enzymes. To better understand the mechanism of restriction, we conduct...

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Detalles Bibliográficos
Autores principales: Lukic, Zana, Hausmann, Stéphane, Sebastian, Sarah, Rucci, Justin, Sastri, Jaya, Robia, Seth L, Luban, Jeremy, Campbell, Edward M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279310/
https://www.ncbi.nlm.nih.gov/pubmed/22078707
http://dx.doi.org/10.1186/1742-4690-8-93