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TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions
BACKGROUND: The TRIM5 proteins are cellular restriction factors that prevent retroviral infection in a species-specific manner. Multiple experiments indicate that restriction activity requires accessory host factors, including E2-enzymes. To better understand the mechanism of restriction, we conduct...
Autores principales: | Lukic, Zana, Hausmann, Stéphane, Sebastian, Sarah, Rucci, Justin, Sastri, Jaya, Robia, Seth L, Luban, Jeremy, Campbell, Edward M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279310/ https://www.ncbi.nlm.nih.gov/pubmed/22078707 http://dx.doi.org/10.1186/1742-4690-8-93 |
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