NADPH Phagocyte Oxidase Knockout Mice Control Trypanosoma cruzi Proliferation, but Develop Circulatory Collapse and Succumb to Infection

(•)NO is considered to be a key macrophage-derived cytotoxic effector during Trypanosoma cruzi infection. On the other hand, the microbicidal properties of reactive oxygen species (ROS) are well recognized, but little importance has been attributed to them during in vivo infection with T. cruzi. In...

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Detalles Bibliográficos
Autores principales: Santiago, Helton C., Gonzalez Lombana, Claudia Z., Macedo, Juan P., Utsch, Lara, Tafuri, Wagner L., Campagnole-Santos, Maria José, Alves, Rosana O., Alves-Filho, José C. F., Romanha, Alvaro J., Cunha, Fernando Queiroz, Teixeira, Mauro M., Radi, Rafael, Vieira, Leda Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279332/
https://www.ncbi.nlm.nih.gov/pubmed/22348160
http://dx.doi.org/10.1371/journal.pntd.0001492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279332/
https://www.ncbi.nlm.nih.gov/pubmed/22348160
http://dx.doi.org/10.1371/journal.pntd.0001492

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