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p53-Dependent Transcriptional Responses to Interleukin-3 Signaling

p53 is critical in the normal response to a variety of cellular stresses including DNA damage and loss of p53 function is a common feature of many cancers. In hematological malignancies, p53 deletion is less common than in solid malignancies but is associated with poor prognosis and resistance to ch...

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Detalles Bibliográficos
Autores principales: Jabbour, Anissa M., Gordon, Lavinia, Daunt, Carmel P., Green, Benjamin D., Kok, Chung H., D'Andrea, Richard, Ekert, Paul G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279357/
https://www.ncbi.nlm.nih.gov/pubmed/22348085
http://dx.doi.org/10.1371/journal.pone.0031428